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Notably, the STEP (Semaglutide Treatment Effect in People with obesity) trials, which specifically examined body composition, demonstrated substantial weight loss compared with placebo (NCT03548935) [53], and reductions in fat mass and visceral adipose tissue were accompanied by decreases in lean mass, although the proportion of lean mass relative to total body mass increased (NCT04074161) [54]

What we know with confidence Tesamorelin reduces visceral fat in HIV-positive patients with lipodystrophy

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For optimal stability, Bacteriostatic Water should be stored at controlled room temperature in a clean, dry environment away from excessive heat and direct light exposure

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