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Animals developed persistent esophagitis with hemorrhagic lesions, thinned epithelium, and chronically reduced sphincter pressures lasting up to 20 months

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Etanercept and infliximab inactivate a cytokine called tumor necrosis factor- (TNF-)

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Mantovani, G., Maccio, A., Madeddu, C., Serpe, R., Massa, E., Dessi, M., Panzone, F., and Contu, P