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Recently, extracellular matrix derived from mesenchymal stem cells were shown to maintain re-differentiation potential of human chondrocytes ( Conclusion In vitro expanding human chondrocytes to a number that is required by the ACI results in the generation of senescent cells

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In addition, although earlier GLP-1 medications have been used safely for decades in people with diabetes, the long-term effects of lifelong use of newer, more potent agonists remain unknown

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