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GLP-1 and GIP receptors are distributed throughout the body, including the pancreas, gastrointestinal tract, cardiovascular system, and central nervous system

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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for managing type 2 diabetes and, at higher doses, for chronic weight management in adults with obesity or overweight with weight-related comorbidities