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The Bottom Line Foundayo (orforglipron) is a genuinely novel development in GLP-1 therapy

Cost is roughly comparable across formats

Retatrutide is a weekly injection that acts on three hormone receptors to support weight loss

Though data is still emerging, it appears that GLP-1 RAs show promise as a potential adjunct medication for IIH patients with benefits that extend beyond weight loss

Researchers sourcing it should understand the quality considerations involved

GLP-1s are incretin-based agents that amplify glucose-stimulated insulin secretion, suppress inappropriate glucagon release, slow gastric emptying, and promote satiety