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They screened six differentially expressed ferroptosis-related genes (IL6, ANGPTL7, CDKN1A, AKR1C3, NOX4, and VLDLR) and constructed a random forest model based on these genes, which demonstrated strong diagnostic performance in the validation dataset, highlighting the close relationship between ferroptosis and immunity in atherosclerosis pathogenesis (61)

The product of this process is primarily the hydroxy free radical, the most poisonous of all ROS

Cell 182 , 388403.e315 (2020)