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Cleveland Clinic explains that starting out with too large of a calorie deficit can lead to side effects like fatigue, headaches, dehydration, nausea and irritability. If you also cut too much protein from your diet, your body may begin breaking down muscle for fuel, which can further impact strength and metabolism. Sleep plays a role too

It is present in virtually every cell of the human body and plays a critical role in numerous physiological processes

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Neuropsychobiology 62, 229234.CrossRefGoogle ScholarPubMed Tramontina, JF, Andreazza, AC, Kauer-Sant'anna, M, Stertz, L, Goi, J, Chiarani, F, Kapczinski, F (2009)