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It facilitates the reciprocal exchange of intracellular glutamate and extracellular cystine in a 1:1 ratio, ushering cystine entry into the cell

10.3390/molecules25245789 13 BrescianiG.ManaiF.DavinelliS.TucciP.SasoL.AmadioM

It stimulates collagen, improves microcirculation, reduces inflammation, and supports hair follicle regeneration, making it one of the most advanced therapies in regenerative dermatology

Patience and consistency essential for meaningful outcomes

Rather than targeting isolated mechanisms, future therapies must consider the convergence of mitochondrial stress, protein aggregation, and neuroinflammation

To date, most clinical studies have been of short duration (412 weeks), and long-term safety data in neurodegenerative populations are lacking (Choi et al., 2011