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In the C-terminus of GLP-2, we observed that it forms a more extensive interaction with the ECL1 of GLP-2R compared to the GLP-1GLP-1R ECL1 interaction (interface area = 791 2 vs 424 2 )
Gould E, Tanapat P, McEwen BS, Flugge G, Fuchs E
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[5] Metformin with GLP-1 RA: Rationale for Consideration in Obese T2D Patients The rationale for combining metformin with a GLP-1 receptor agonist lies in their complementary mechanisms across metabolic tissues
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