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The most affected product categories include chips & savory snacks (-11%), sweet bakery items (-9%) and soft drinks (-7%), which translates into short-to-medium term losses of USD 7.5-8 bn within these segments in the US market

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(78) found that a three-month co-administration of Bifidobacterium lactis Probio-M8 with calcium and calcitriol improved bone metabolism in patients, as evidenced by decreased levels of bone turnover markers such as alkaline phosphatase (ALP) and osteocalcin (OC)

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The enzymes responsible for this digestion (pepsin in the stomach, trypsin and chymotrypsin from the pancreas in the small intestine) are highly efficient and rapidly degrade most therapeutic peptides to pharmacologically inactive fragments before they can act on mucosal tissue

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