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They possess remarkable properties, including multipotency, self-renewal, and easy clinical availability

A few highlights: Accelerated eGFR decline during the year preceding a heart failure event Slower decline afterward but still exacerbated A parallel between eGFR slope and NYHA class, suggesting the kidney may be signaling congestion early These findings call for a shift in practice: instead of relying on static eGFR thresholds, tracking its trajectory over time could help us identify at-risk patients sooner and intervene before hospitalization

Yet the close tally and contrary staff recommendation make it unsafe to predict the exact final wording, conditions, or timing

PMC 1221580