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G., Paul, A., Chakraborty, A., & Kundu, S

While low-dose paraxanthine showed a trend toward improvement in older animals, it didn't reach statistical significance (p = 0.07)

Conceptually, its practical significance has been ascribed to its particular role in the Selyes stress response [3,7,8], as well as to its resolving of activities of the braingut and gutbrain axes [7,12]