Last reviewed: May 25, 2026 Last updated: May 25, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
It offers the same dual-hormone benefits as Mounjaro but is prescribed for patients with obesity or overweight, regardless of diabetes status
Along with preclinical data indicating that long-acting GIPR agonists act in the brain to decrease body weight and food intake via GIPR signalling in inhibitory -aminobutyric acid-producing (GABAergic) neurons 5,6,7 , and by mitigating the emetic effects of GLP-1R agonism 8,9 , GIPRGLP-1R co-agonism has been established as a highly effective strategy for the management of obesity, type 2 diabetes and MASH
Before starting semaglutide, tell your healthcare provider if you have any other medical conditions, including if you: Have or have had problems with your pancreas or kidneys
A maintenance plan should consider: Protein intake that supports muscle and satiety
Those numbers are trial averages, not guarantees