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Individualized risk assessment, patient education, and careful dose titration are essential for optimizing long-term tolerability

ABSTRACT Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as game-changers across the cardiovascularkidneymetabolic (CKM) spectrum: overweight/obesity, type 2 diabetes mellitus (T2DM) and associated chronic kidney disease (CKD) and cardiovascular disease (CVD)

Mistake 2: skipping titration steps Impatient researchers sometimes jump from 2mg directly to 8mg, or from 4mg straight to 12mg, reasoning that they tolerated the lower dose well and want faster results

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"Our position is that more supply, especially at a reasonable price, is needed right now, not less," Noom CEO Geoff Cook told CNBC in an interview