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[DOI] [PubMed] [Google Scholar] 118.Rihal V., Khan H., Kaur A., Singh T.G

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In response to stress, low expression of PGC-1 results in a reduction in ATP synthesis and an increase in ROS production, which in turn leads to dopamine neuron loss or damage

If your vitamin B12 deficiency is not caused by a lack of vitamin B12 in your diet, youll usually need to have an injection of B12 (hydroxocobalamin) every 2 to 3 months for maintenance