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In the STEP clinical trials, patients weighing over 100 kg (220 lbs) tended to need the full 2.4 mg maintenance dose for optimal results, while those under 80 kg (176 lbs) sometimes achieved their goals at 1.0 or 1.7 mg

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The progression of placebo-treated group and the lack of deterioration in the ALC-treated group on MoCA-K may demonstrate carnitine-placebo differences