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Kwieciska-Pirg J, Skowron K, Bogiel T, Biaucha A, Przekwas J, Gospodarek-Komkowska E

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Gastrointestinal side effects are the most commonly reported adverse effects of tirzepatide, with clinical trials showing dose-dependent rates: nausea (20-33%), diarrhea (12-23%), vomiting (9-16%), constipation (11-17%), and abdominal pain

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Given that SOCS proteins inhibit insulin/IGF-1 signaling, they are able to elicit insulin resistance, a condition which is known to be associated with aging

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