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A maintenance-dose arm runs alongside the program, evaluating a new 4 mg weekly maintenance dose in addition to the 9 mg and 12 mg arms

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We looked at [alanine transaminase] and [aspartate aminotransferase] levels throughout the study, and similar to other GLP-1 receptor agonists, the levels were reduced throughout the study and stayed that way for 72 weeks, Alfaris said

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Fifth, GLP-1RAs protect against cardiomyocyte apoptosis under diabetic conditions via activating the leucine zipper motif (APPL 1 )-AMPK-PPAR axis and the AMPK-TXNIP pathway [80, 161]