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GLP-1, GIP, exendin-4 and liraglutide had suppressive effects on oxLDL-induced foam cell formation, which is linked with the suppression of infiltrated macrophage foam cells in atherosclerotic plaques, resulting in repressed atherosclerotic plaque formation

Many patients taking GLP-1 receptor agonists for diabetes or weight management report improvements in joint pain, prompting questions about whether these medications directly address musculoskeletal symptoms

These clinical trials aim to show a reduction in insulin resistance and improved glycemic management when GLP-1s are used in addition to insulin