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Description

Its mechanism can be summarized as: Activation of the GHRH receptor cAMP/PKA signaling inside pituitary somatotrophs Endogenous growth hormone release Downstream IGF-1 pathway activation DAC-dependent differences in duration and exposure Importantly, CJC-1295 is not growth hormone

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The gene expression work by Pickart and Campbell, published through the Broad Institutes Connectivity Map dataset analysis, represents a significant contribution to understanding GHK-Cus mechanism

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