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Its mechanisms include: Nitric oxide modulation regulates blood flow and inflammation at injury sites Growth factor upregulation increases EGF, FGF, and VEGF expression Gut-brain axis signaling systemic effects mediated through the GI tract Dopaminergic system interaction neuroprotective properties BPC-157 is unique among healing peptides because it works systemically through the gut , even when administered locally

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10.1046/j.1471-4159.2000.0751907.x 174

Food-derived bioactive peptides in human health: Challenges and opportunities