10.1126/scisignal.2003386 124 Navarro-PandoJ
No reason to expect significant rebound or withdrawal
No published study has linked it to tumor promotion, but if you have an active malignancy, the theoretical risk of feeding blood vessels to a tumor is worth taking seriously
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Under CMS-0057-F (effective January 1, 2026), payers must respond within 7 calendar days for standard requests and 72 hours for urgent/expedited requests
Injecting close to the affected area is believed by some to provide more localized effects, though systemic distribution occurs regardless of injection site