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In GIP/GIPR binding models, Ile 12 , which is surrounded by hydrophilic components, 32 might not interact with GIPR
doi: 10.2337/dc19-0578 169 BornerTDe JongheBCHayesMR
Ala 18 The mutation of GIP His 18 to Ala reinforced its insulinotropic effect
Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation, which typically diminish over time with dose titration
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