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Halperin understands that people might be tempted to seek out lower-cost alternatives, but she recommends that patients work with a healthcare provider who has experience in treating obesity, even if they cant get access to a specific medication at the moment

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Increasing the dosage quickly or starting retatrutide at high doses can result in serious side effects

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The Lancet

Thus, these findings provide important mechanistic and therapeutic insights into the disruption of intestinal homeostasis and postprandial glucose dysregulation, particularly in obesity and aging