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doi: 10.1186/s11658-025-00700-2 379 ChenXWangYWangJNCaoQCSunRXZhuHJet al

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Who Should Consider Oral vs Injectable?# Oral may be preferred for: Patients with needle phobia or injection anxiety Patients who travel frequently Those seeking lower-cost options Patients comfortable with daily dosing First-line therapy before escalating to injectables Injectable may be preferred for: Patients seeking maximum weight loss Those who prefer less frequent dosing (weekly or monthly) Patients who struggle with daily medication adherence Those who need dual or triple agonist mechanisms Conclusion# The oral GLP-1 revolution is well underway

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All Other Customers, 2021 to 2025 Exhibit 184: McKesson, Revenues from Rite Aid, 2016 to 2025 Exhibit 185: Cardinal Health, Revenues from Optum Rx, 2016 to 2024 Exhibit 186: McKesson, U.S

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