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For example, controlled trials in diabetic polyneuropathy have employed 600 mg of ALA injected IV once daily (often given as an infusion over 30-60 minutes) for periods of 2-4 weeks, with significant efficacy observed in reducing neuropathic symptoms compared to placebo

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doi: 10.1111/j.1365-2265.2005.02325.x 139 WeiLSunShongXZhangJXuYZhuHet al

In one embodiment, the nanoparticles are suitable for use with hydrophobic active principles

Studies designed to investigate BPC 157's effect on discogenic pain models, on nerve compression injuries, and on inflammatory markers in spinal tissue could provide the crucial data needed to move this field forward