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500 mcg / 5,000 = 0.1 mL = 10 units

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However, metformin also exerts anticancer effects and is thought to do this through both AMPK-dependent and AMPK-independent mechanisms 116

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This study was carried out in accordance with the recommendations of the respective Institutional Review Boards (IRBs), described below with written informed consent from parents of subjects and assent where appropriate