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doi: 10.1007/s13300-012-0015-6 55

Thazhath SS, et al

High levels of UA inhibit the growth of the pancreatic -cell lines (INS-1 and RIN-m5F) in a time- and dose-dependent manner via the ROS-AMPK-ERK signaling pathway [31]

It participates in the conversion of homocysteine to methionine and the metabolism of methylmalonic acid, both crucial for energy production at the cellular level

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