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Written by Ali Rza Akn Microbiome Scientist, Author & Founder of Next-Microbiome Ali Rza Akn is a microbiome scientist with nearly 30 years of experience in translational biotechnology, systems biology, and applied microbiome research, spanning discovery, preclinical development, and clinical-stage translation
Our patient was diagnosed with severe GSSD after neonatal onset, with symptoms including hemolytic anemia, hyperbilirubinemia and severe metabolic acidosis (intractable), urine-organic acid analysis results suggestive of the presence of 5-oxoprolinuria, and imaging results suggestive of central nervous system damage and developmental retardation in the infant at follow-up
Additionally, delayed gastric emptying could worsen symptoms in patients with stricturing disease or increase obstruction risk, making tolerability a significant concern
J Chem Theory Comput 11:436450
[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Basavarajappa B.S., Subbanna S
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