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Nutr & diabetes
Research article Peer reviewed Non-randomized Observational study People
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For researchers transitioning from semaglutide or tirzepatide to retatrutide, the dose schedule requires a fresh start
Pre-existing risk factors : Individuals with established osteoporosis, previous fragility fractures, advanced age (particularly postmenopausal women), low baseline BMI, or those taking medications that affect bone metabolism (such as corticosteroids) may be more susceptible to bone density changes during weight loss
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