Most studies have found a decrease in GLP-1 secretion in obese individuals [92], and some studies have found no difference in GLP-1 levels between obese and normal-weight controls [93]
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Maybe you have a few days where your sleep is interrupted, or you have a particularly stressful deadline at work
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Oxidative stress
The dosing schedule starts at 0.25mg weekly for the first month, then titrates up gradually to the maintenance dose