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They produce distinct metabolic effects that influence weight loss magnitude, body composition changes, glycemic control, and side effect patterns

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There should be a low threshold for treating possible urinary tract infections

In 2005, the first GLP-1 agonist, exenatide, was approved for the management of Type 2 diabetes mellitus (T2DM) [6]

Tirzepatides SURPASS programme demonstrated superior HbA1c reductions compared to semaglutide in head-to-head type 2 diabetes trials [2]

The chyme present in the terminal antrum is forced retrograde across the central opening of the peristaltic wave into the relaxing middle antrum