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Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/akt-dependent activation of Nrf2

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The importance of DNL in NAFLD is further supported by studies, showing that in obese patients with NAFLD, approximately 26% of hepatic triglycerides were derived from DNL and that these patients were unable to regulate DNL when transitioning from fasting to fed state [40]

doi:10.1056/NEJMoa2307563 Tao Z, Deng X, Guo B, Ding Z, Fan Y

2021, Jun;54(6):125775.e8 Shoraka S, Samarasinghe AE, Ghaemi A, Mohebbi SR