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If you have IBS-C (constipation-predominant): This is where challenges can arise

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Earlier concerns regarding acute pancreatitis and pancreatic cancer have largely been alleviated by long-term randomized trials that have not confirmed a causal association, although reporting biases and diagnostic complexity remain considerations, and continued pharmacovigilance is recommended

This is particularly evident in specific cardiovascular conditions such as heart failure with preserved ejection fraction (HFpEF), for which effective treatments are scarce

Chun YS, Passot G, Nishioka Y, Katkhuda R, Arvide EM, Benzerdjeb N, Lopez J, Kopetz SE, Maru DM, Vauthey JN

Our findings reveal that all evaluated GLP-1 RAs were associated with a significant increased risk of nausea