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Ayuda a descomponer los compuestos que contribuyen al estrs oxidativo

These changes subsequently inhibit ferroptosis in ovarian granulosa cells, ultimately improving IR and ovarian function, which contributes to its therapeutic efficacy in PCOS (52)

Access this article Similar content being viewed by others Abbreviations ARE: Antioxidant response element ATP: Adenosine 5-triphosphate ASC: Apoptosis-associated speck-like protein containing a CARD bZIP: Basic-region leucine zipper CNC: Cap n collar CNS: Central nervous system DEM: Diethyl Maleate Gclc: Glutamate cysteine ligase catalytic subunit Gclm: Glutamate cysteine ligase regulatory subunit HO-1: Heme oxygenase-1 Keap1: Kelch-like ECH-associated protein 1 LPS: Lipopolysaccharide NF-B: Nuclear factor-B NLRP3: NLR family pyrin domain containing protein 3 Nqo1: NAD(P)H:quinone oxidoreductase 1 Nrf2: Nuclear factor-erythroid-2-related factor 2 PRR: Pattern recognition receptor ROS: Reactive oxygen species References Ahmed SM, Luo L, Namani A, Wang XJ (1863) Tang X (2017) Nrf2 signaling pathway: pivotal roles in inflammation

10.1096/fj.201800831R 25 ChoiE

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