CD47 is primarily expressed on neurons and astrocytes, whereas its receptor SIRP is located on microglia
Interestingly, the lung GSH (Figure 3B) was maintained at the same level throughout the CS exposure
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Furthermore, the peptides may be linked to other functional and/or structural moieties such as carbohydrates, fats, proteins or peptides, antibodies, receptors, hormones, cytotoxic substances, marker substances, dyes, radioactive labels, immunomodulatory agents, drugs, carriers, targeting or signalling substances, etc
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The remarkable weight loss and glucose-lowering results achieved by the dual peptides paved the way for triple GIP/GLP-1/glucagon receptor triagonists with the hope that the new combinatorial approaches provide further synergistic metabolic effects