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GLP-1R is not expressed in AgRP neurons but is expressed in POMC neurons [55], indicating that its effect on AgRP neurons is indirect and originates from other regions [50,55,56]

Rather than blocking reuptake to keep serotonin in the synapse longer, GLP-1 agonists appear to enhance the overall activity of serotonergic neurons

The company describes this as a "3-in-1 Formula" that addresses what it calls "Performance + Desire + Connection." According to published pricing, the 5mg starting dose is listed at $119 per month for 8 troches