To protect muscle during treatment: Encourage strength training and physical activity Ensure adequate protein intake Use tools to monitor body composition, not just weight This helps patients maintain functionality while still achieving the metabolic benefits of treatment
The effects of GLP-1s increase postprandial insulin secretion from pancreatic -cells, suppress glucagon secretion from -cells, slow gastric emptying, and reduce appetite (Gross)
Parker VER, Robertson D, Wang T et al (2020) Efficacy, safety, and mechanistic insights of cotadutide, a dual receptor glucagon-like peptide-1 and glucagon agonist
The doses of these drugs used with cells were based on previous data [34,35,36]
Waist-to-Hip Ratio Calculator Measure body fat distribution and metabolic risk
The TRIUMPH-4 trial data showing improved pain scores and metabolic markers alongside weight loss underscores that the benefits of these peptides extend well beyond the number on a scale