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The consensus, if one exists, is this: split dosing is a pharmacologically reasonable modification that has not been clinically validated

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Reporting their findings in The BMJ [2] (online, 20 October 2016 ) , the team found that there was a similar level of breast cancer risk among the 498 patients who used GLP-1 analogues, such as liraglutide and exenatide, and the 2,422 patients who used DPP-4 inhibitors, at 4.4 and 3.4 per 1,000 person-years, respectively