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The variables that had the most significant effect on the ICER were the discount rate (ICER range: $30,857.45-$57,117.71), the annual cost of oral semaglutide (ICER range: $32,004.67-$47,701.77), absolute therapeutic effect on systolic blood pressure (SBP) (ICER range: $35,539.79-$45,856.96), duration of treatment (ICER range: $34,536.96-$44,763.10), and HbA1c treatment effect (ICER range: $36,071.16-$455,01.91)

Studies show that semaglutide continues to help control appetite and improve blood sugar over time

Lastly, the goal of semaglutide is to improve patients overall health and decrease the chance of patients developing chronic health conditions that include hypertension, diabetes, cardiovascular disease, joint pain, sleep apnea, and lastly depression and anxiety

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Gonzalez-Alvarez J, Sos-Pena R