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In clinical trials with participants with obesity, 5 mg, 10 mg, or 15 mg of tirzepatide once weekly provided substantial and sustained reductions in body weight over 72 weeks [22]
Clinical trials show semaglutide users lose 15-22% body weight over 68 weeks, and tirzepatide users achieve 22-28% weight loss over similar periods
299 , C1461C1467 (2010)
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The most common side effects are mild and gastrointestinal, such as nausea or constipation, especially when starting