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However, this does not typically result in their death due to the capacity of Glu to synthesize glutathione (GSH), a vital antioxidant that plays a crucial role in cancer cells and their resistance to oxidative stress [45]

Biological Chemistry, 390(3), 191214

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In addition, crizotinib potently inhibited HGF-stimulated endothelial cell survival or invasion and serum-stimulated tubulogenesis in vitro, suggesting that this agent also exhibits antiangiogenic properties [71, 72]

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