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These somatic and signaling abnormalities are accompanied by increased oxidative stress associated with mitochondrial dysfunction both in ASD and AD [353]

To view or add a comment, sign in Renal Tubular Acidosis (RTA) A High Yield Nephrology Overview Renal Tubular Acidosis (RTA) is a group of disorders characterized by normal anion gap (hyperchloremic) metabolic acidosis resulting from the kidneys inability to maintain acid-base balance due to impaired hydrogen ion (H) secretion or bicarbonate (HCO) reabsorption, despite relatively preserved glomerular filtration

This increased demand can potentially create relative deficiencies in these co-factors, even if their levels were previously adequate

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