Increased microvascular permeability brought on by ROS causes inflammatory cells to migrate and exacerbates the inflammatory process (Hecquet and Malik, 2009)
However, persistent burning, stinging, or increasing irritation suggests the concentration may be too high or your skin needs more time to adjust
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Under physiological conditions, the rate of DA oxidation is slow, and the cellular antioxidant machinery can cope with the formation of highly reactive products from DA oxidation [13]
Liu, Wu et al., 2021) have been shown to decrease inflammation in mouse model systems
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