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HR: 0.66) and reduced all-cause mortality (HR: 0.53) compared to users of DPP-4i [96]

These medications work by mimicking the action of the naturally occurring GLP-1 hormone, which enhances insulin secretion, suppresses glucagon release, slows gastric emptying, and promotes satiety

Known to interact with the oxytocin receptor (OXTR), this peptide has been extensively studied in non-clinical models of bonding behavior, stress-response signaling, cognitive pathway mechanisms, autonomic responses, and reproductive mechanisms

Together, these effects create what some clinicians describe as metabolic youth, meaning the body performs more like it did years earlier