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Under different ferroptosis induction conditions, p53 promotes ferroptosis partly by inhibiting SLC7A11 expression, while p53 deficiency promotes ferroptosis resistance by SLC7A11 upregulation
PMID: 30340338
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Neuroprotective effects: Some studies suggest that KPV may have neuroprotective properties, potentially reducing neuroinflammation and supporting neural health
To overcome these limitations, ABT-263 (Navitoclax), a derivative of ABT-737, was developed as an orally bioavailable pan-BCL inhibitor (62)
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