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For example, if you have a deficiency and need regular B12 injections, hydroxocobalamin can be given once every 3 months, whereas cyanocobalamin would need to be given every month

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In some cases, injections may be given daily or several times per week at the beginning of therapy, and then the interval may be extended or switched to oral tablets once vitamin levels and symptoms improve

The administration of live vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids

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Lawson DH, Murray RM, Parker JLW, Hay G