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(Nature, 1996) -- the foundational paper establishing cortistatin's discovery and its selective promotion of SWS when administered intracerebroventricularly in rats

The successful transmission of neural signals from one cell to another in animals relies on the mutual conversion of chemical signals (neurotransmitters) and electrical signals, where ion fluxes are induced by neurotransmitters and the release of neurotransmitters is dependent on electrical signals 1,2,42

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Subsequently, they modulated cytokines release, such as IL-6, TNF-, and IL-1

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Effect of thyme oil and thymol dietary supplementation on the antioxidant status and fatty acid composition of the ageing rat brain