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Someone stopping these medications doesnt have the same control over their obesity, and their weight can increase. What to expect Nearly 12% of Americans about one in eight have used GLP-1 drugs for weight loss, according to a 2025 report from RAND, a nonprofit research organization
Large clinical trials have not identified bone loss as a significant adverse effect, though the weight loss these medications produce may indirectly affect bone density in some individuals
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Questions about practical considerations: What is the titration schedule, and how long before I reach the target dose
Knop, et al (2007)
directly compared GLP-1 receptor agonists to insulin or sulfonylureas, whereas Chang et al
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