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Furthermore, preliminary tests allowed the determination of the maximum control current and the appropriate time extent of the irradiation in order to keep the sample temperature in the physiological range

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This glutamine-driven TCA cycle activity supports critical biosynthetic pathways, including fatty acid synthesis and the production of non-essential amino acids, to sustain tumor growth and proliferation

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Ferroptosis is regulated by distinct molecular pathways and was shown to play an important role in degenerative and neoplastic diseases 26